Total arterial revascularization in a child with familial homozygous hypercholesterolemia
نویسندگان
چکیده
منابع مشابه
Coronary revascularization in a child with homozygous familial hypercholesterolemia.
Familial hypercholesterolemia (FH) is a genetic disease caused by a mutation in low-density lipoprotein (LDL) receptor gene. It causes various presentations including tendon xanthoma and cardiac manifestations. Herein, we present a young patient with homozygous FH (HFH) who presented with dyspnea and chest pain caused by coronary arteries stenosis and treated with coronary artery bypass graft (...
متن کاملHomozygous familial hypercholesterolemia with generalized arterial disease.
OBJECTIVE This report describes the clinical features and management of an 11-year-old boy with end-stage homozygous familial hypercholesterolemia (hoFH) and generalized arterial disease. CLINICAL PRESENTATION AND INTERVENTION The patient presented with recurrent anginal episodes. On examination, he was found to have multiple planar and tendinous xanthomas, an (LDL) cholesterol level of 24.6 ...
متن کاملPatient With Homozygous Familial Hypercholesterolemia
Familial hypercholesterolemia (FH), caused by a defect in the low density lipoprotein (LDL) receptor, results in high plasma concentrations of LDL cholesterol due to both overproduction and delayed catabolism of LDL FH is also associated with significantly lower levels of plasma high density lipoprotein cholesterol and apolipoprotein (apo) A-I in both heterozygous and homozygous patients. Howev...
متن کاملHomozygous familial hypercholesterolemia.
We report a rare case of homozygous familial hypercholesterolemia (HoFH), a 22-year-old Malay woman who presented initially with minor soft tissue injury due to a cycling accident. She was then incidentally found to have severe xanthelasma and hypercholesterolemia (serum TC 15.3 mmol/L and LDL-C 13.9 mmol/L). She was referred to the Specialized Lipid Clinic and was diagnosed with familial hyper...
متن کاملTen-year follow-up of coronary revascularization in a pediatric case with homozygous familial hypercholesterolemia
A six-year-old boy was admitted to our clinic with a history of chest pain in May 2006. He was diagnosed with HFH six months ago, and was scheduled for liver transplantation. He received medical therapy including atorvastatin 40 mg daily and ezetimibe 10 mg daily. With the treatment, total cholesterol was 768 mg/dL, LDL cholesterol 679 mg/dL, high-density lipoprotein (HDL) cholesterol 24 mg/dL,...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2005
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2004.03.054